Application of double filtration plasmapheresis to cynomolgus monkeys: surgical techniques and a pilot study of pig fetal kidney transplantation

Application of double filtration plasmapheresis to cynomolgus monkeys: surgical techniques and a pilot study of pig fetal kidney transplantation

ABSTRACT Purpose: To detail a technique to implant a double-lumen catheter to remove anti-pig antibodies. We transplanted fetal pig kidneys into cynomolgus monkeys using a double filtration plasma exchange (DFPP) protocol. Methods: Two approaches for double-lumen catheter insertion in monkeys (3–9...

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Main Authors: Genki Watanabe, Maiko Horikawa, Izumi Yamamoto, Tomohisa Endo, Takashi Watanabe, Akinori Hiratsuka, Tsuyoshi Takamura, Kenji Matsui, Naoto Matsumoto, Yatsumu Saito, Hiroshi Sasaki, Akihiko Kiyoshi, Takao Kuroda, Makoto Inoue, Eiji Kobayashi, Takashi Yokoo
Format: Article
Language:English
Published: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2025-07-01
Series:Acta Cirúrgica Brasileira
Subjects:
Transplantation, Heterologous
Plasmapheresis
Macaca fascicularis
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502025000100230&lng=en&tlng=en
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