Effects of azithromycin on alleviating airway inflammation in asthmatic mice by regulating airway microbiota and metabolites

Effects of azithromycin on alleviating airway inflammation in asthmatic mice by regulating airway microbiota and metabolites

ABSTRACT Asthma is a chronic respiratory disease with increasing global prevalence, often linked to disrupted airway microbiota. Azithromycin has shown promise in asthma treatment, but whether its effect is owing to its antimicrobial capacity remains largely unknown. A house dust mite (HDM)-induced...

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Main Authors: DanHui Huang, Lingyan Xie, Tingyue Luo, Lishan Lin, QianNan Ren, Zhaojin Zeng, Haohua Huang, Hua Liao, XiaoDan Chang, Yuehua Chen, Haijin Zhao, Shaoxi Cai, Hangming Dong
Format: Article
Language:English
Published: American Society for Microbiology 2025-03-01
Series:Microbiology Spectrum
Subjects:
asthma
azithromycin
airway microbiota
sphingomyelin metabolism
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02217-24
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https://journals.asm.org/doi/10.1128/spectrum.02217-24

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