Topological data analysis of pattern formation of human induced pluripotent stem cell colonies

Abstract Understanding the multicellular organization of stem cells is vital for determining the mechanisms that coordinate cell fate decision-making during differentiation; these mechanisms range from neighbor-to-neighbor communication to tissue-level biochemical gradients. Current methods for quan...

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Bibliographic Details
Main Authors: Iryna Hartsock, Eunbi Park, Jack Toppen, Peter Bubenik, Elena S. Dimitrova, Melissa L. Kemp, Daniel A. Cruz
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-90592-1
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