Forward genetic screen in zebrafish identifies new fungal regulators that limit host-protective Candida-innate immune interaction

Forward genetic screen in zebrafish identifies new fungal regulators that limit host-protective Candida-innate immune interaction

ABSTRACT Candida is one of the most frequent causes of bloodstream infections, and our first line of defense against these invasive infections is the innate immune system. The early immune response is critical in controlling Candida albicans infection, but C. albicans has several strategies to evade...

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Bibliographic Details
Main Authors: Bailey A. Blair, Emma Bragdon, Gursimran Dhillon, Nnamdi Baker, Lena Stasiak, Mya Muthig, Pedro Miramon, Michael C. Lorenz, Robert T. Wheeler
Format: Article
Language:English
Published: American Society for Microbiology 2025-05-01
Series:mBio
Subjects:
Candida
innate immunity
phagocytosis
macrophages
neutrophils
virulence determinants
Online Access:https://journals.asm.org/doi/10.1128/mbio.00529-25
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https://journals.asm.org/doi/10.1128/mbio.00529-25

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