Promoter methylation and increased expression of PD-L1 in patients with active tuberculosis

The PD-1/PD-L1 pathway plays a pivotal role in T cell activity and is involved in the pathophysiology of Mycobacterium tuberculosis (MTB) infection. DNA methylation is a mechanism that modulates PD-L1 expression in cancer cells. However, its effect on PD-L1 expression in macrophages after MTB infect...

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Main Authors: Yen-Han Tseng, Sheng-Wei Pan, Jhong-Ru Huang, Chang-Ching Lee, Jung-Jyh Hung, Po-Kuei Hsu, Nien-Jung Chen, Wei-Juin Su, Yuh-Min Chen, Jia-Yih Feng
Format: Article
Language:English
Published: Shared Science Publishers OG 2024-07-01
Series:Microbial Cell
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Online Access:http://microbialcell.com/researcharticles/2024a-tseng-microbial-cell
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