Noninvasive prognostication of hepatocellular carcinoma based on cell-free DNA methylation.

<h4>Background</h4>The current noninvasive prognostic evaluation methods for hepatocellular carcinoma (HCC), which are largely reliant on radiographic imaging features and serum biomarkers such as alpha-fetoprotein (AFP), have limited effectiveness in discriminating patient outcomes. Ide...

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Main Authors: Ran Hu, Benjamin Tran, Shuo Li, Mary L Stackpole, Weihua Zeng, Yonggang Zhou, Andrew Melehy, Saeed Sadeghi, Richard S Finn, Xianghong Jasmine Zhou, Wenyuan Li, Vatche G Agopian
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0321736
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