Development and validation of a visual nomogram for predicting clinically significant prostate cancer in negative mpMRI using 68Ga-PSMA PET/CT

Development and validation of a visual nomogram for predicting clinically significant prostate cancer in negative mpMRI using 68Ga-PSMA PET/CT

Abstract Multi-parametric magnetic resonance imaging (mpMRI) is a valuable medical technology for detecting clinically significant prostate cancer (csPCa). The diagnostic accuracy of mpMRI for csPCa in negative mpMRI (PI-RADS 1–2) remains suboptimal, underscoring the need for improvements for csPCa....

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Main Authors: Wei Hu, ShiKuan Guo, XiangLiang Meng, FuLi Wang, ShuaiJun Ma, Chao Zhang, JingYi Wang, Lei Yuan, LongLong Zhang, YuMing Jing, Jian Chen, HaoZhong Hou, Yang Wang, KeYing Zhang, Yu Li, Fei Kang, DongHui Han, HongQian Guo, JingLiang Zhang, Jing Ren, WeiJun Qin
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Prostate cancer
68Ga-PSMA PET/CT
MpMRI
Nomogram
Diagnosis
Online Access:https://doi.org/10.1038/s41598-025-12312-z
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https://doi.org/10.1038/s41598-025-12312-z

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