Integrating network pharmacology and in vivo model to reveal the cardiovascular protective effects of kaempferol-3-O-rutinoside on heart failure

Kaempferol-3-O-rutinoside (KR) has an excellent cardioprotective effect, but its mechanism of action is not clear. Network pharmacology was used to predict the signaling pathways, whereas molecular docking was used for preliminary validation of KR binding to targets. AMI model rats with ligated left...

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Bibliographic Details
Main Authors: Guo Lu-Qin, Zhou Lan, Li Sheng-Nan, Bai Juan, Shi Ling-Li, Hua Fang, Zhou Peng
Format: Article
Language:English
Published: Sciendo 2025-03-01
Series:Acta Pharmaceutica
Subjects:
Online Access:https://doi.org/10.2478/acph-2025-0001
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