PEG-PLGA nanoparticles deposited in Pseudomonas aeruginosa and Burkholderia cenocepacia

PEG-PLGA nanoparticles deposited in Pseudomonas aeruginosa and Burkholderia cenocepacia

In our prior research, polymer nanoparticles (NPs) containing tobramycin displayed robust antibacterial efficacy against biofilm-embedded Pseudomonas aeruginosa (P. aeruginosa) and Burkholderia cenocepacia (B. cenocepacia) cells, critical pathogens in cystic fibrosis. In the current study, we invest...

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Bibliographic Details
Main Authors: Tinatini Tchatchiashvili, Helena Duering, Lisa Mueller-Boetticher, Christian Grune, Dagmar Fischer, Mathias W. Pletz, Oliwia Makarewicz
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Journal of Pharmaceutical Analysis
Subjects:
Polyester
Tobramycin
Poly(ethylene glycol)
Antimicrobial activity
Cystic fibrosis
Bacterial membrane
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177924000273
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