The distribution of allelic and genotypic frequencies of N-Acetyltransferase-2 variants in an Argentine population

The distribution of allelic and genotypic frequencies of N-Acetyltransferase-2 variants in an Argentine population

Introduction: Arylamine N-acetyltransferase-2 (NAT-2) is a key human enzyme in drug detoxification and elimination. Mutations in NAT-2 affect the activity of anti-tuberculosis drugs and result in three different phenotypes: rapid (RA), intermediate (IA) and slow acetylators (SA). Methodology: The...

Full description

Saved in:
Bibliographic Details
Main Authors: Julián Gabriel Chamorro, Jorge P Castagnino, Rosa M Musella, Ana Frias, Federico Manuel Aranda, Gabriela Fernanda de Larrañaga
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2012-09-01
Series:Journal of Infection in Developing Countries
Subjects:
NAT-2
polymorphism
tuberculosis
acetylator profile
prevalence
Online Access:https://jidc.org/index.php/journal/article/view/2111
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://jidc.org/index.php/journal/article/view/2111

Similar Items