Integrated network pharmacology and in vivo experiments to reveal the anti-inflammatory mechanism of Qinghuo Rougan Formula in uveitis

Integrated network pharmacology and in vivo experiments to reveal the anti-inflammatory mechanism of Qinghuo Rougan Formula in uveitis

BackgroundUveitis is a complex intraocular inflammatory disease and pathology results from the continuous production of proinflammatory cytokines in the optical axis. Qinghuo Rougan Formula (QHRGF), a traditional Chinese medicine (TCM) is now used to treat uveitis with desirable effect. However, the...

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Bibliographic Details
Main Authors: Changying Jing, Yaqi Sun, Hongsheng Bi, Junguo Guo, Cong Ren, Jike Song, Beibei Wang, Qingmei Tian, Dadong Guo, Pengjuan He, Lijie Li, Xiaofeng Xie
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Molecular Biosciences
Subjects:
uveitis
network pharmacology
WGCNA
Qinghuo Rougan Formula
systems biology
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2025.1632027/full
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https://www.frontiersin.org/articles/10.3389/fmolb.2025.1632027/full

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