LINE-1 Methylation sustains telomere length in pregnant women: effects on pregnancy failure

LINE-1 Methylation sustains telomere length in pregnant women: effects on pregnancy failure

Abstract Background Pregnancy loss is one of the most common adverse events during the first weeks of gestation, and the incidence increases with maternal age and in presence of selected risk factors. Nonetheless, no risk factors have been identified in most cases, considering these cases unexplaine...

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Main Authors: Donato Gemmati, Fabio Scarpellini, Francesca Salvatori, Elisabetta D’Aversa, Roberto Marci, Roberta Capucci, Bianca Antonica, Miriana Grisafi, Elisa Turato, Joanne Vanessa Vargas, Paola Secchiero, Giorgio Zauli, Ajay V. Singh, Veronica Tisato
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Clinical Epigenetics
Subjects:
Pregnancy loss
Epigenetics
DNA-methylation
Telomere length
LINE-1
Aging
Online Access:https://doi.org/10.1186/s13148-025-01937-6
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https://doi.org/10.1186/s13148-025-01937-6

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