Plug-and-display nanoparticle immunization of the core epitope domain induces potent neutralizing antibody and cellular immune responses against PEDV

Plug-and-display nanoparticle immunization of the core epitope domain induces potent neutralizing antibody and cellular immune responses against PEDV

Porcine epidemic diarrhea virus (PEDV), an enteric coronavirus, is widely spread worldwide and causes huge economic losses. The effective measure to control the viral infection is to develop ideal vaccines. Here, the collagenase equivalent domain (COE) of PEDV was displayed on the surface of nanopar...

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Bibliographic Details
Main Authors: Minghui Li, Yilan Chen, Siqiao Wang, Xueke Sun, Yongkun Du, Siyuan Liu, Ruiqi Li, Zejie Chang, Peiyang Ding, Gaiping Zhang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-09-01
Series:Journal of Integrative Agriculture
Subjects:
PEDV
nanoparticle multimerization
mucosal immunization
germinal center
Online Access:http://www.sciencedirect.com/science/article/pii/S209531192400193X
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http://www.sciencedirect.com/science/article/pii/S209531192400193X

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