Systematic analysis of cotranscriptional RNA folding using transcription elongation complex display

Abstract RNA can fold into structures that mediate diverse cellular functions. Understanding how RNA primary sequence directs the formation of functional structures requires methods that can comprehensively assess how changes in an RNA sequence affect its structure and function. Here we have develop...

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Bibliographic Details
Main Authors: Skyler L. Kelly, Eric J. Strobel
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-57415-3
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