Potential therapeutic effects of interleukin-1 receptor type 1 antagonist and the ethyl acetate fraction of Murraya exotica leaves against κ-carrageenan induced vein thrombosis in rats

Potential therapeutic effects of interleukin-1 receptor type 1 antagonist and the ethyl acetate fraction of Murraya exotica leaves against κ-carrageenan induced vein thrombosis in rats

Background: Thrombosis is the primary cause of cardiovascular diseases, cerebral ischemia, hypoxia, tissue softening, and necrosis. One of the best models used to assess antithrombotic and thrombolytic drugs is the κ-carrageenan induced vein tail thrombosis rats model. Purpose: The purpose of this s...

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Main Authors: Asmaa F. Aboul Naser, Wessam M. Aziz, Amal M. El-Feky, Marwa M. Elbatanony, Noha N. Nasr, Yomna R. Ahmed, Sylvia E. Shaker, Wagdy K.B. Khalil, Manal A. Hamed
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Phytomedicine Plus
Subjects:
Vein thrombosis
κ-carrageenan
IL-1receptor antagonist
Murraya exotica, Gene expression
Inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S2667031325000685
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