Sex-specific spirometry effects of adult COPD polygenic score in children with asthma

Abstract Chronic obstructive pulmonary disease (COPD) is a leading cause of death and disability globally. While genetic and environmental risk factors are known, these insights have not yet resulted in individualized prevention strategies. Polygenic scores (PS) have enhanced our understanding of ge...

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Bibliographic Details
Main Authors: Jelte Kelchtermans, Joseph M. Collaco, Huiqi Qu, Frank Mentch, Sharon A. McGrath-Morrow, Hakon Hakonarson
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-94804-6
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