Veillonella parvula outer membrane vesicles increase ICAM-1+ neutrophils exhibiting elevated NET formation via ROS–PAD4 signaling

Veillonella parvula outer membrane vesicles increase ICAM-1+ neutrophils exhibiting elevated NET formation via ROS–PAD4 signaling

BackgroundVeillonella parvula (V. parvula), as an anaerobic Gram-negative coccus, produces outer membrane vesicles (OMVs) to promote bacterial colonization and periodontitis progress. Neutrophils are the first immune cells during bacterial stimulation, while neutrophil extracellular traps (NETs) are...

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Bibliographic Details
Main Authors: Lina Xu, Yiting Jiang, Xuri Zhao, Jiabao Zhuang, Huiwen Chen, Teng Li, Zhiyan He, Wei Zhou, Zhongchen Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Veillonella parvula
outer membrane vesicles
ICAM-1
neutrophils
NETs
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1540634/full
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https://www.frontiersin.org/articles/10.3389/fcimb.2025.1540634/full

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