Blood osmolytes such as sugar can drive brain fluid flows in a poroelastic model

Abstract The glymphatic system of fluid flow through brain tissue may clear amyloid-β during sleep and as such underlie the need for sleep. Dysfunctional glymphatic transport has been implicated in pathological conditions ranging from stroke and dementia to psychiatric illnesses. To date, the fastes...

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Bibliographic Details
Main Authors: Peter A. R. Bork, Michael Gianetto, Evan Newbold, Lauren Hablitz, Tomas Bohr, Maiken Nedergaard
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-024-80593-x
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