Efficacy and Safety of Sacubitril/Valsartan Versus Amlodipine in Japanese Patients With Essential Hypertension: A Randomized, Multicenter, Open‐Label, Noninferiority Study (PARASOL Study)

Efficacy and Safety of Sacubitril/Valsartan Versus Amlodipine in Japanese Patients With Essential Hypertension: A Randomized, Multicenter, Open‐Label, Noninferiority Study (PARASOL Study)

ABSTRACT Sacubitril/valsartan, an angiotensin receptor‐neprilysin inhibitor, has demonstrated a superior blood pressure‐lowering effect compared with renin‐angiotensin system inhibitors in several clinical trials. However, there has been no available evidence on the comparison between sacubitril/val...

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Bibliographic Details
Main Authors: Koichi Yamamoto, Daisuke Yarimizu, Ayano Shimanishi, Shunsuke Eguchi, Kazuma Iekushi, Yoichi Takami, Yoichi Nozato, Kazuomi Kario, Hiromi Rakugi
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:The Journal of Clinical Hypertension
Subjects:
ambulatory blood pressure monitoring
angiotensin receptor‐neprilysin inhibitor
calcium channel blocker
essential hypertension
sacubitril/valsartan
Online Access:https://doi.org/10.1111/jch.14938
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https://doi.org/10.1111/jch.14938

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