Investigating the causal role of serum metabolites in substance use disorder risk: a study integrating Mendelian randomization and synthesis analysis

Abstract Objective This study aimed to explore how serum metabolites affect the risk of substance use disorders (SUD). Methods In the initial stage, Mendelian randomization was applied to assess the relationship between 1,400 serum metabolites and SUD. Inverse variance weighting, the Wald ratio odds...

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Bibliographic Details
Main Authors: WeiXiong Xu, DanDan Xie, ZhenZhu Zhang, PiBo Du, YongJian Ye, XuBo Dai
Format: Article
Language:English
Published: Springer 2025-08-01
Series:Discover Mental Health
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Online Access:https://doi.org/10.1007/s44192-025-00275-6
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