Serum expression signature of TUG1, MALAT1, miR-483, and miR-141 and their targets TGF-β1 and STAT3 in severe male factor infertility

Serum expression signature of TUG1, MALAT1, miR-483, and miR-141 and their targets TGF-β1 and STAT3 in severe male factor infertility

Abstract Long non-coding RNAs and microRNAs have evolved as biomarkers and specific therapeutic targets for male infertility. We investigated the seminal plasma and serum expression profiles of TUG1, MALAT1, miR-483, and miR-141 and their targets TGF-β1 and STAT3 in severe male factor infertility. T...

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Bibliographic Details
Main Authors: Mahmoud A. Senousy, Olfat G. Shaker, Ahmed Gamal, Nesreen M. Aboraia, Ghada Ayeldeen
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Azoospermia
Infertility
LncRNA
MicroRNA
Oligozoospermia
Online Access:https://doi.org/10.1038/s41598-025-03231-0
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https://doi.org/10.1038/s41598-025-03231-0

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