Fusarium spp. and Aspergillus flavus infection induces pathogen-specific and pathogen-independent host immune response in patients with fungal keratitis

Fusarium spp. and Aspergillus flavus infection induces pathogen-specific and pathogen-independent host immune response in patients with fungal keratitis

IntroductionFungal keratitis, caused primarily by Fusarium spp. and Aspergillus flavus, is a significant cause of corneal blindness, particularly in tropical regions. Current antifungal agents like natamycin and voriconazole have limited efficacy, underscoring the need for a deeper understanding of...

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Bibliographic Details
Main Authors: Shreya Dinesh, Lalitha Prajna, Prajna Namperumalsamy Venkatesh, Kuppamuthu Dharmalingam, Bharanidharan Devarajan
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
fungal keratitis (FK)
differential gene expression
pathogen specific host immune response
IL-17 signalling pathway
RT-qPCR analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1560628/full
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https://www.frontiersin.org/articles/10.3389/fcimb.2025.1560628/full

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