Shared gene signatures and molecular mechanisms link ankylosing spondylitis and rheumatoid arthritis

Shared gene signatures and molecular mechanisms link ankylosing spondylitis and rheumatoid arthritis

Abstract Ankylosing spondylitis (AS) and rheumatoid arthritis (RA) are closely related autoimmune diseases with shared mechanisms that remain unclear. This study aims to identify shared molecular signatures and hub genes underlying the co-occurrence of AS and RA using clinical and transcriptomic dat...

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Main Authors: Boli Qin, Xiaopeng Qin, Jie Ma, Chenxing Zhou, Tianyou Chen, Jichong Zhu, Chengqian Huang, Shaofeng Wu, Rongqing He, Songze Wu, Sitan Feng, Jiarui Chen, Jiang Xue, Wendi Wei, Tengxiang Long, Quan Pan, Kechang He, Zhendong Qin, Tiejun Zhou, Jiayan Jiang, Xinli Zhan, Chong Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
MYO1F
Neutrophil infiltration
Shared mechanisms
Transcriptomics
Online Access:https://doi.org/10.1038/s41598-025-07300-2
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https://doi.org/10.1038/s41598-025-07300-2

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