CD4+T and CD8+T Cells in Uterus Exhibit Both Selective Dysfunction and Residency Signatures

CD4+T and CD8+T Cells in Uterus Exhibit Both Selective Dysfunction and Residency Signatures

Unlike T cells in other tissues, uterine T cells must balance strong immune defense against pathogens with tolerance to semiallogeneic fetus. Our previous study fully elucidated the characteristics of γδT cells in nonpregnant uterus and the mechanism modulated by estrogen. However, comprehensive kno...

Full description

Saved in:

Bibliographic Details
Main Authors:	Shuangpeng Kang, Shuiping Jin, Xueying Mao, BinSheng He, Changyou Wu
Format:	Article
Language:	English
Published:	Wiley 2024-01-01
Series:	Journal of Immunology Research
Online Access:	http://dx.doi.org/10.1155/2024/5582151
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Both CD4+ and CD8+ Lymphocytes Participate in the IFN-γ Response to Filamentous Hemagglutinin from Bordetella pertussis in Infants, Children, and Adults
by: Violette Dirix, et al.
Published: (2012-01-01)

CD3+CD8+CD28− T Lymphocytes in Patients with Lupus Nephritis
by: Marcelina Żabińska, et al.
Published: (2016-01-01)

Retracted: Role of CD4+T, CD8+T Cells, and CD4+T/CD8+T Cell Ratio in Gastric Cancer and Its Clinical Significance
by: Applied Bionics and Biomechanics
Published: (2023-01-01)

Effector, Memory, and Dysfunctional CD8+ T Cell Fates in the Antitumor Immune Response
by: John Reiser, et al.
Published: (2016-01-01)

EDF1 accelerates ganglioside GD3 accumulation to boost CD52-mediated CD8+ T cell dysfunction in neuroblastoma
by: Di Li, et al.
Published: (2025-02-01)

Ex Vivo Restimulation of Human PBMC Expands a CD3+CD4-CD8-γδ+ T Cell Population That Can Confound the Evaluation of CD4 and CD8 T Cell Responses to Vaccination
by: B. J. Sedgmen, et al.
Published: (2013-01-01)

Establishment of Normal Reference Intervals for CD3+, CD4+, CD8+, and CD4+ to CD8+ Ratio of T Lymphocytes in HIV Negative Adults from University of Gondar Hospital, North West Ethiopia
by: Addisu Gize, et al.
Published: (2014-01-01)

Osteoclasts and CD8 T Cells Form a Negative Feedback Loop That Contributes to Homeostasis of Both the Skeletal and Immune Systems
by: Zachary S. Buchwald, et al.
Published: (2013-01-01)

Repetitive antigen stimulation in the periphery dictates the composition and recall responses of brain-resident memory CD8+ T cells
by: Madison R. Mix, et al.
Published: (2025-02-01)

Sézary Syndrome with CD4/CD8 Double-Negative Neoplastic T Cells in Peripheral Blood
by: Yuki Kageyama, et al.
Published: (2021-01-01)

Suppressed Programmed Death 1 Expression on CD4+ and CD8+ T Cells in Psoriatic Patients
by: Joanna Bartosińska, et al.
Published: (2017-01-01)

T CD3+CD8+ Lymphocytes Are More Susceptible for Apoptosis in the First Trimester of Normal Human Pregnancy
by: Dorota Darmochwal-Kolarz, et al.
Published: (2014-01-01)

The Effects of Aloe vera Cream on the Expression of CD4+ and CD8+ Lymphocytes in Skin Wound Healing
by: Yos Adi Prakoso, et al.
Published: (2018-01-01)

Serum levels of soluble IL-2R, CD4 and CD8 in bronChial asthma
by: G. Di Lorenzo, et al.
Published: (1995-01-01)

Contradictory Effect of Lymphocyte Therapy and Prednisolone Therapy on CD3+CD8+CD56+ Natural Killer T Population in Women with Recurrent Spontaneous Abortion
by: Fatemeh Rezayat, et al.
Published: (2023-07-01)

Estimation of CD8 Parameter Level in Thalassemia Patients
by: Sajad Abd-Alsahib, et al.
Published: (2022-11-01)

Mesangial Cells Exhibit Features of Antigen-Presenting Cells and Activate CD4+ T Cell Responses
by: Hongyu Yu, et al.
Published: (2019-01-01)

Antigen-Specific Tissue-Resident Memory T Cells in the Respiratory System Were Generated following Intranasal Vaccination of Mice with BCG
by: Qiongli Wu, et al.
Published: (2021-01-01)

Prevalence of Oral Manifestations and Their Association with CD4/CD8 Ratio and HIV Viral Load in South India
by: Sharma Gaurav, et al.
Published: (2011-01-01)

Low CD4/CD8 Ratio in Bronchus-Associated Lymphoid Tissue Is Associated with Lung Allograft Rejection
by: K. V. Shenoy, et al.
Published: (2012-01-01)

Role of CD4+ T and CD8+ T Lymphocytes-Mediated Cellular Immunity in Pathogenesis of Chronic Obstructive Pulmonary Disease
by: Weilin Xue, et al.
Published: (2022-01-01)

The CD4/CD8 ratio is associated with T lymphocyte functions in long-term virally suppressed patients with HIV
by: Qing Xiao, et al.
Published: (2025-01-01)

Activated CD27+PD-1+ CD8 T Cells and CD4 T Regulatory Cells Dominate the Tumor Microenvironment in Refractory Celiac Disease Type II
by: Tessa Dieckman, et al.
Published: (2025-01-01)

Intrahepatic CD161hiCD8+T Cell Recruitment Has a Pathogenetic Potential in Chronic HBV Infection
by: Jianfei Li, et al.
Published: (2025-01-01)

Single-cell landscape of dynamic changes in CD8+ T cells, CD4+ T cells and exhausted T cells in hepatocellular carcinoma
by: Rongqiang Liu, et al.
Published: (2025-02-01)

Serum Levels of Soluble IL-2R, CD4 and CD8 in Chronic Active HCV Positive Hepatitis
by: C. Caruso, et al.
Published: (1994-01-01)

The Impact of Nutritional Status and Tumor-Infiltrating Lymphocytes (CD4+ and CD8+) on Chemotherapy Response in Colorectal Cancer Patients
by: Lukman K, et al.
Published: (2025-01-01)

Myeloid cell-derived apCAFs promote HNSCC progression by regulating proportion of CD4+ and CD8+ T cells
by: Feilong Ren, et al.
Published: (2025-01-01)

The Pathogenic Role of Expanded CD8⁺CD28<sup>null</sup> Angiogenic T Cells in ANCA-Associated Vasculitis
by: Haomiao Shen, et al.
Published: (2024-12-01)

Epigenetic Control of Interferon-Gamma Expression in CD8 T Cells
by: Patrícia S. de Araújo-Souza, et al.
Published: (2015-01-01)

Advanced Ovarian Dysgerminoma Infiltrating Both Ovaries and Uterus in a 7-Year-Old Girl
by: Nexhmi Hyseni, et al.
Published: (2014-01-01)

Level of CD8 T Lymphocytes Activation in HIV-Infected Pregnant Women: In the Context of CD38 and HLA-DR Activation Markers
by: Stanslaus Musyoki, et al.
Published: (2014-01-01)

Probiotics Can Boost the Antitumor Immunity of CD8+T Cells in BALB/c Mice and Patients with Colorectal Carcinoma
by: Jie Mao, et al.
Published: (2020-01-01)

Intratumoural CD8+ CXCR5+ follicular cytotoxic T cells have prognostic value and are associated with CD19+ CD38+ B cells and tertiary lymphoid structures in colorectal cancer
by: Fangze Wei, et al.
Published: (2024-12-01)

Both Freshly Prepared and Frozen-Stored Amniotic Membrane Cells Express the Complement Inhibitor CD59
by: Ágnes Füst, et al.
Published: (2012-01-01)

Antigen-Independent Maturation of CD2, CD11a/CD18,CD44, and CD58 Expression on Thymic Emigrants inFetal and Postnatal Sheep
by: Deborah A. Witherden, et al.
Published: (1995-01-01)

CD169 Expression in Lymph Nodes is Associated with Increased Infiltration of CD8+ T Cells in Tumors: A Systematic Review and Meta-Analysis
by: Yong Wang, et al.
Published: (2024-01-01)

Diagnostic Value of CD25, CD69, and CD134 on Tuberculosis-Specific Antigen-Stimulated CD4+ T Cells for Tuberculous Pleurisy
by: Hanlu Shi, et al.
Published: (2023-01-01)

NKG2C+CD57+ Natural Killer Cell Expansion Parallels Cytomegalovirus-Specific CD8+ T Cell Evolution towards Senescence
by: John Heath, et al.
Published: (2016-01-01)

Coinfection by Hepatitis C Is Strongly Associated with Abnormal CD4/CD8 Ratio in HIV Patients under Stable ART in Salvador, Brazil
by: Clara Brites-Alves, et al.
Published: (2015-01-01)