Understanding the clinical morbidity and mortality of fibrodysplasia ossificans progressiva: a systematic literature review

Abstract Background Fibrodysplasia ossificans progressiva (FOP) is an autosomal dominant ultra-rare disease characterized by progressive episodic multi-focal heterotopic ossification of skeletal muscle, ligaments, tendons, and fascia. Comprehensive characterization and understanding of the natural d...

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Bibliographic Details
Main Authors: Hind Harrak, Susan Rhee, Amal Souttou, Sarah J. O’Meara, Caitlin Knox
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Orphanet Journal of Rare Diseases
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Online Access:https://doi.org/10.1186/s13023-025-03763-8
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