Druggable Molecular Networks in <i>BRCA1/BRCA2</i>-Mutated Breast Cancer

Druggable Molecular Networks in <i>BRCA1/BRCA2</i>-Mutated Breast Cancer

Mutations in the tumor suppressor genes <i>BRCA1</i> and <i>BRCA2</i> are associated with the triple-negative breast cancer phenotype, particularly aggressive and hard-to-treat tumors lacking estrogen, progesterone, and human epidermal growth factor receptor 2. This research...

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Bibliographic Details
Main Authors: Francesca Pia Carbone, Pietro Ancona, Stefano Volinia, Anna Terrazzan, Nicoletta Bianchi
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Biology
Subjects:
BRCA1
BRCA2
mutations
breast cancer
phytoestrogens
PARPi
Online Access:https://www.mdpi.com/2079-7737/14/3/253
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