Determination of the Roles of <i>H. pylori</i> Outer Membrane Virulence Factors and Pyroptosis-Associated NLRP3, ASC, Caspase-1, Gasdermin D, IL-1β, and IL-18 in Ulcer and Gastritis Pathogenesis

Determination of the Roles of <i>H. pylori</i> Outer Membrane Virulence Factors and Pyroptosis-Associated NLRP3, ASC, Caspase-1, Gasdermin D, IL-1β, and IL-18 in Ulcer and Gastritis Pathogenesis

Background: This study aims to investigate the association between pyroptosis and the outer membrane virulence factor of <i>H. pylori</i> in patients with gastritis and ulcers. Methods: DNA, RNA, and protein were extracted from a single tissue sample taken from the antrum region of the s...

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Main Authors: Yaren Buyukcolak-Cebeci, Emel Timucin, Sumeyye Akcelik-Deveci, Nesteren Mansur-Ozen, Tuana Aydinlar, Arzu Tiftikci, Sinem Oktem-Okullu
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Biology
Subjects:
<i>Helicobacter pylori</i>
outer membrane virulence factor
pyroptosis
programmed cell death
<i>H. pylori</i>-related gastritis
<i>H. pylori</i>-related ulcer
Online Access:https://www.mdpi.com/2079-7737/14/6/634
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