Claudin5a is required for proper inflation of Kupffer's vesicle lumen and organ laterality.

Left-right asymmetric organ development is critical to establish a proper body plan of vertebrates. In zebrafish, the Kupffer's vesicle (KV) is a fluid-filled sac which controls asymmetric organ development, and a properly inflated KV lumen by means of fluid influx is a prerequisite for the asy...

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Bibliographic Details
Main Authors: Jeong-Gyun Kim, Sung-Jin Bae, Hye Shin Lee, Ji-Hyeon Park, Kyu-Won Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0182047&type=printable
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