Gut virome dysbiosis impairs antitumor immunity and reduces 5-fluorouracil treatment efficacy for colorectal cancer

Gut virome dysbiosis impairs antitumor immunity and reduces 5-fluorouracil treatment efficacy for colorectal cancer

IntroductionDespite the established influence of gut bacteria, the role of the gut virome in modulating colorectal cancer (CRC) patient chemotherapy response remains poorly understood. In this study, we investigated the impact of antiviral (AV) drug-induced gut virome dysbiosis on the efficacy of 5-...

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Bibliographic Details
Main Authors: Hui Huang, Ying Yang, Xiaojiao Wang, Biao Wen, Xianglan Yang, Wei Zhong, Qiurong Wang, Feng He, Jun Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Oncology
Subjects:
colorectal cancer
5-fluorouracil
gut virome
fecal microbiota transplantation
immune response
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1501981/full
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https://www.frontiersin.org/articles/10.3389/fonc.2024.1501981/full

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