Factors Associated with Medication Nonadherence among Hypertensives in Ghana and Nigeria

Background. Blood pressure (BP) control is poor among hypertensives in many parts of sub-Saharan Africa. A potentially modifiable factor for control of BP is medication nonadherence (MNA); our study therefore aimed to determine factors associated with MNA among hypertensives in Ghana and Nigeria. Me...

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Main Authors: Vincent Boima, Adebowale Dele Ademola, Aina Olufemi Odusola, Francis Agyekum, Chibuike Eze Nwafor, Helen Cole, Babatunde L. Salako, Gbenga Ogedegbe, Bamidele O. Tayo
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:International Journal of Hypertension
Online Access:http://dx.doi.org/10.1155/2015/205716
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author Vincent Boima
Adebowale Dele Ademola
Aina Olufemi Odusola
Francis Agyekum
Chibuike Eze Nwafor
Helen Cole
Babatunde L. Salako
Gbenga Ogedegbe
Bamidele O. Tayo
author_facet Vincent Boima
Adebowale Dele Ademola
Aina Olufemi Odusola
Francis Agyekum
Chibuike Eze Nwafor
Helen Cole
Babatunde L. Salako
Gbenga Ogedegbe
Bamidele O. Tayo
author_sort Vincent Boima
collection DOAJ
description Background. Blood pressure (BP) control is poor among hypertensives in many parts of sub-Saharan Africa. A potentially modifiable factor for control of BP is medication nonadherence (MNA); our study therefore aimed to determine factors associated with MNA among hypertensives in Ghana and Nigeria. Methodology. We conducted a multicenter cross-sectional study. Patients were recruited from Korle-Bu Hospital (n=120), Ghana; and University of Port Harcourt Teaching Hospital, (n=73) Apapa General Hospital Lagos (n=79) and University College Hospital Ibadan (n=85), Nigeria. Results. 357 hypertensive patients (42.6% males) participated. MNA was found in 66.7%. Adherence showed correlation with depression (r=-0.208, P<0.001), concern about medications (r=-0.0347, P=0.002), and knowledge of hypertension (r=0.14, P=0.006). MNA was associated with formal education (P=0.001) and use of herbal preparation (P=0.014). MNA was found in 61.7% of uninsured participants versus 73.1% of insured participants (P=0.032). Poor BP control was observed in 69.7% and there was significant association between MNA and poor BP control (P=0.006). Conclusion. MNA is high among hypertensives in Ghana and Nigeria and is associated with depression, concern about hypertensive medications, formal education, and use of herbal preparations. The negative association between health insurance and MNA suggests interplay of other factors and needs further investigation.
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spelling doaj-art-0b58283d7ddf4e1caa13c1a66a85f8c92025-02-03T06:11:13ZengWileyInternational Journal of Hypertension2090-03842090-03922015-01-01201510.1155/2015/205716205716Factors Associated with Medication Nonadherence among Hypertensives in Ghana and NigeriaVincent Boima0Adebowale Dele Ademola1Aina Olufemi Odusola2Francis Agyekum3Chibuike Eze Nwafor4Helen Cole5Babatunde L. Salako6Gbenga Ogedegbe7Bamidele O. Tayo8School of Medicine and Dentistry, University of Ghana, P.O. Box 4236, Accra, GhanaDepartment of Paediatrics, Faculty of Clinical Sciences, College of Medicine, University of Ibadan, Ibadan PMB 5017, Oyo State, NigeriaDepartment of Medicine, General Hospital, Randle Avenue, Apapa PMB 1014, Lagos, NigeriaDepartment of Medicine, Korle Bu Teaching Hospital, P.O. Box 77, Accra, GhanaCardiology Division, Department of Medicine, University of Port Harcourt Teaching Hospital, Port Harcourt PMB 6173, Rivers State, NigeriaDepartment of Population Health, NYU School of Medicine, 227 E. 30th Street, 6th Floor, New York, NY 10016, USADepartment of Medicine, Faculty of Clinical Sciences, College of Medicine, University of Ibadan, Ibadan PMB 5017, Oyo State, NigeriaDepartment of Population Health, NYU School of Medicine, 227 E. 30th Street, 6th Floor, New York, NY 10016, USADepartment of Public Health Sciences, Stritch School of Medicine, Loyola University Chicago, 2160 South First Avenue, Maywood, IL 60153, USABackground. Blood pressure (BP) control is poor among hypertensives in many parts of sub-Saharan Africa. A potentially modifiable factor for control of BP is medication nonadherence (MNA); our study therefore aimed to determine factors associated with MNA among hypertensives in Ghana and Nigeria. Methodology. We conducted a multicenter cross-sectional study. Patients were recruited from Korle-Bu Hospital (n=120), Ghana; and University of Port Harcourt Teaching Hospital, (n=73) Apapa General Hospital Lagos (n=79) and University College Hospital Ibadan (n=85), Nigeria. Results. 357 hypertensive patients (42.6% males) participated. MNA was found in 66.7%. Adherence showed correlation with depression (r=-0.208, P<0.001), concern about medications (r=-0.0347, P=0.002), and knowledge of hypertension (r=0.14, P=0.006). MNA was associated with formal education (P=0.001) and use of herbal preparation (P=0.014). MNA was found in 61.7% of uninsured participants versus 73.1% of insured participants (P=0.032). Poor BP control was observed in 69.7% and there was significant association between MNA and poor BP control (P=0.006). Conclusion. MNA is high among hypertensives in Ghana and Nigeria and is associated with depression, concern about hypertensive medications, formal education, and use of herbal preparations. The negative association between health insurance and MNA suggests interplay of other factors and needs further investigation.http://dx.doi.org/10.1155/2015/205716
spellingShingle Vincent Boima
Adebowale Dele Ademola
Aina Olufemi Odusola
Francis Agyekum
Chibuike Eze Nwafor
Helen Cole
Babatunde L. Salako
Gbenga Ogedegbe
Bamidele O. Tayo
Factors Associated with Medication Nonadherence among Hypertensives in Ghana and Nigeria
International Journal of Hypertension
title Factors Associated with Medication Nonadherence among Hypertensives in Ghana and Nigeria
title_full Factors Associated with Medication Nonadherence among Hypertensives in Ghana and Nigeria
title_fullStr Factors Associated with Medication Nonadherence among Hypertensives in Ghana and Nigeria
title_full_unstemmed Factors Associated with Medication Nonadherence among Hypertensives in Ghana and Nigeria
title_short Factors Associated with Medication Nonadherence among Hypertensives in Ghana and Nigeria
title_sort factors associated with medication nonadherence among hypertensives in ghana and nigeria
url http://dx.doi.org/10.1155/2015/205716
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