Direct prion neuroinvasion following inhalation into the nasal cavity

Direct prion neuroinvasion following inhalation into the nasal cavity

ABSTRACT Inhalation of prions into the nasal cavity is an efficient route of infection. Following inhalation of infectious prions, animals develop disease with a similar incubation period compared with per os exposure, but with greater efficiency. To identify the reason for this increased efficiency...

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Bibliographic Details
Main Authors: Anthony E. Kincaid, Melissa D. Clouse, Shawn M. Magrum, Jason C. Bartz
Format: Article
Language:English
Published: American Society for Microbiology 2024-12-01
Series:mSphere
Subjects:
prion disease
neuroinvasion
prion diagnostics
nasal cavity
trigeminal ganglia
trigeminal nerve
Online Access:https://journals.asm.org/doi/10.1128/msphere.00863-24
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https://journals.asm.org/doi/10.1128/msphere.00863-24

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