Natural killer cell biology and therapy in multiple myeloma: challenges and opportunities

Natural killer cell biology and therapy in multiple myeloma: challenges and opportunities

Abstract Despite therapeutic advancements, multiple myeloma (MM) remains incurable. NK cells have emerged as a promising option for the treatment of MM. NK cells are heterogenous and typically classified based on the relative expression of their surface markers (e.g., CD56 and CD16a). These cells el...

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Main Authors: Kamlesh Bisht, Aimee Merino, Rob Igarashi, Laurent Gauthier, Marielle Chiron, Alexandre Desjonqueres, Eric Smith, Edward Briercheck, Rizwan Romee, Evren Alici, Eric Vivier, Michael O’Dwyer, Helgi van de Velde
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Experimental Hematology & Oncology
Subjects:
Multiple myeloma
Natural killer cells
Natural killer cell activating receptor
Natural killer cell inhibitory receptor
Immunomodulation
Natural killer cell engagers
Online Access:https://doi.org/10.1186/s40164-024-00578-4
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https://doi.org/10.1186/s40164-024-00578-4

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