Berberine chloride inhibits proliferation and angiogenesis in triple-negative breast cancer by down-regulating HIF-1α/VEGF/Ang pathway

Berberine chloride inhibits proliferation and angiogenesis in triple-negative breast cancer by down-regulating HIF-1α/VEGF/Ang pathway

In triple-negative breast cancer, intratumoral hypoxia drives tumor progression via HIF-1α-mediated angiogenesis. The study aims to analyze the efficacy of berberine chloride on tumor proliferation and angiogenesis in triple-negative breast cancer mediated by HIF-1α. The triple-negative breast canc...

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Bibliographic Details
Main Authors: Nishmaa Sulthan Mohideen, Venkatalakshmi Ranganathan, Fazeela Mahaboob Begum S. Mohamed Nainar
Format: Article
Language:English
Published: Bangladesh Pharmacological Society 2025-05-01
Series:Bangladesh Journal of Pharmacology
Subjects:
Ang pathway
Angiogenesis
Berberine chloride
HIF-1α pathway
MTT assay
Triple-negative breast cancer
Online Access:https://www.banglajol.info/index.php/BJP/article/view/80837
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