A Novel Protein Purification Approach Using Elastin-Like Polypeptides (ELP) With His-Tag Assistance

Protein purification is essential for drug development, antibody production, and structural biology. We propose a cost-effective chromatography method using elastin-like polypeptide (ELP) as an aggregating core. In this approach, a chilled (target protein)-ELP fusion is loaded onto an immobilized me...

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Bibliographic Details
Main Authors: Young Chae, Han Shin
Format: Article
Language:English
Published: Bio-protocol LLC 2025-06-01
Series:Bio-Protocol
Online Access:https://bio-protocol.org/en/bpdetail?id=5342&type=0
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