ICOS-expressing CAR-T cells mediate durable eradication of triple-negative breast cancer and metastasis

Background The failure of conventional therapies and the propensity for recurrence and metastasis make triple-negative breast cancer (TNBC) a formidable challenge with grim prognoses and diminished survival rates. Immunotherapy, including immune checkpoint blockade and chimeric antigen receptor (CAR...

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Bibliographic Details
Main Authors: Hui Zhang, Fei Yu, Xinxin Chen, Haiyan Ye, Tao Zeng, Lixue Cao, Haojie Peng, Yanzhen Chen, Baijin Xia, Jialing Guo
Format: Article
Language:English
Published: BMJ Publishing Group 2024-11-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/12/11/e010028.full
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