Relative mtDNA copy number in embryo spent culture medium is not a reliable biomarker of human embryo aneuploidy

Relative mtDNA copy number in embryo spent culture medium is not a reliable biomarker of human embryo aneuploidy

Mitochondrial DNA (mtDNA) from embryonic cells is released into the spent culture medium (SCM) during cellular processes, providing a potential biomarker of embryo health. Analysing mtDNA levels in SCM enables a non-invasive evaluation of embryo quality and potential developmental abnormalities. In...

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Main Authors: Sasipat Teerawongsuwan, Kodchakorn Wiangwised, Nattapavee Ngampiyakul, Nitid Wanikorn, Panida Boonnithipaisit, Panyada Khiuhok, Phanthitra Aekudompong, Amarin Narkwichean, Sirinun Pongmayteegul, Ruttachuk Rungsiwiwut
Format: Article
Language:English
Published: Bioscientifica 2025-04-01
Series:Reproduction and Fertility
Subjects:
embryo spent culture medium
mitochondrial dna copy number
chromosome abnormality
fragmentation
Online Access:https://raf.bioscientifica.com/view/journals/raf/6/2/RAF-25-0001.xml
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