Alveolar macrophages maintain tissue localization and gain enhanced anti-tumor activity in Lewis lung carcinoma-reprogrammed lung microenvironment

Alveolar macrophages maintain tissue localization and gain enhanced anti-tumor activity in Lewis lung carcinoma-reprogrammed lung microenvironment

The role of alveolar macrophages (AMs) in lung carcinogenesis has been extensively studied, yielding significant insights. However, the status of AMs in tumor-bearing lungs remains incompletely characterized. Using orthotopic Lewis Lung Carcinoma (LLC) mouse models, we found that tumors induced an i...

Full description

Saved in:
Bibliographic Details
Main Authors: Mengfei Ren, Jiaxiang Dou, Qian Yue, Liqin Ma, Hang Yu, Shengwen Shang, Shijie Wang, Jian Wang, Tingting Li, Fengqi Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
tumor microenvironment
alveolar macrophages
lung inflammation
Lewis lung carcinoma
extra-tumoral lung microenvironment
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1616514/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2025.1616514/full

Similar Items