HMG Box-containing Protein 1 (HBP1) Protects Against Pancreatic Injury in Acute Pancreatitis but Promotes Neoplastic ProgressionSummary

HMG Box-containing Protein 1 (HBP1) Protects Against Pancreatic Injury in Acute Pancreatitis but Promotes Neoplastic ProgressionSummary

Background & Aims: Pancreatitis is an inflammatory disease of the exocrine pancreas and a known risk factor for pancreatic ductal adenocarcinoma (PDAC). Previously, we identified HMG-box transcription factor 1 (HBP1) as a potential master transcription factor (TF) in the early progression of...

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Main Authors: Seung-Won Lee, Taelor Ekstrom, Elise C. Manalo, Shangyuan Ye, Mark Berry, Dmytro Grygoryev, Malwina Szczepaniak, Jinho Lee, Carlos Origel Marmolejo, Syber Haverlack, Juyoung Lee, Vidhi M. Shah, Dove Keith, John L. Muschler, Koei Chin, Rosalie C. Sears, Stuart P. Weisberg, Terry Morgan, Jungsun Kim
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
Autophagy
HMG Box-containing Protein 1 (HBP1)
Pancreatic Injury
Pancreatitis
PanINs Initiation
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X25000773
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