Furin inhibits HSCs activation and ameliorates liver fibrosis by regulating PTEN‐L/PINK1/parkin mediated mitophagy in mouse
Abstract Hepatic Stellate cells (HSCs) play an important role during liver fibrosis progression; more and more evidence indicates that mitophagy greatly regulates HSCs activation. HSCs mitophagy mainly depends on the classical PINK1/Parkin pathway, which can be strongly regulated by phosphatase PTEN...
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| Main Authors: | Yan‐Wei Song, Yu‐Hua Zhu, Ming‐Ze Ma |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-05-01
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| Series: | FASEB BioAdvances |
| Subjects: | |
| Online Access: | https://doi.org/10.1096/fba.2024-00221 |
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