Furin inhibits HSCs activation and ameliorates liver fibrosis by regulating PTEN‐L/PINK1/parkin mediated mitophagy in mouse

Abstract Hepatic Stellate cells (HSCs) play an important role during liver fibrosis progression; more and more evidence indicates that mitophagy greatly regulates HSCs activation. HSCs mitophagy mainly depends on the classical PINK1/Parkin pathway, which can be strongly regulated by phosphatase PTEN...

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Bibliographic Details
Main Authors: Yan‐Wei Song, Yu‐Hua Zhu, Ming‐Ze Ma
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:FASEB BioAdvances
Subjects:
Online Access:https://doi.org/10.1096/fba.2024-00221
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