Novel 3,19-(N-Phenyl-3-(4-fluorophenyl)-pyrazole) Acetal of Andrographolide Promotes Cell Cycle Arrest and Apoptosis in MDA-MB-231 Breast Cancer Cells

Novel 3,19-(N-Phenyl-3-(4-fluorophenyl)-pyrazole) Acetal of Andrographolide Promotes Cell Cycle Arrest and Apoptosis in MDA-MB-231 Breast Cancer Cells

<b>Background:</b> Natural products play a crucial role in cancer treatment due to their ability to selectively target cancer cells. Andrographolide, a major constituent of <i>Andrographis paniculata</i>, exhibits potential anticancer properties. Considering the pharmacologic...

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Main Authors: Siva Kumar Rokkam, Shahjalal Chowdhury, Yashwanth Inabathina, Lakshminath Sripada, Srinivas Nanduri, Balasubramanyam Karanam, Nageswara Rao Golakoti
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Pharmaceuticals
Subjects:
pyrazole acetals
andrographolide
isoandrographolide
anticancer
antioxidant
Online Access:https://www.mdpi.com/1424-8247/18/7/1026
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