A computational approach to mycolic acid biosynthesis disruption in mycobacterium tuberculosis via molluscan metabolites as KasA inhibitors

Abstract The ongoing global health challenge posed by Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), is exacerbated by the emergence of drug-resistant strains. This study explores the potential of inhibiting the KasA protein, a key component of the bacterium’s type II fatty ac...

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Bibliographic Details
Main Authors: Abdullah R. Alanzi, Fatimah Mohammed Alsulais, Bayan Abdullah Alhaidhal
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-13329-0
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