Crosstalk between CD180-overexpression macrophages and glioma cells worsens patient survival through malignant phenotype promotion and immunosuppressive regulation

Crosstalk between CD180-overexpression macrophages and glioma cells worsens patient survival through malignant phenotype promotion and immunosuppressive regulation

Abstract Background Understanding the molecular mechanisms in immunosuppressive regulation is crucial for improving immunotherapeutic strategies. Macrophages, the major immune cells in tumor microenvironment (TME), play a dual role in tumor progression. CD180, primarily expressed in macrophages, rem...

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Bibliographic Details
Main Authors: Wen Wang, Junsheng Li, Qiheng He, Chenglong Liu, Zhiyao Zheng, Bojian Zhang, Siqi Mou, Wei Sun, Jizong Zhao
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Molecular Medicine
Subjects:
CD180
Glioma
Macrophage
Immunotherapy
Biomarker
Online Access:https://doi.org/10.1186/s10020-024-01029-w
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https://doi.org/10.1186/s10020-024-01029-w

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