Free carnitine and branched chain amino acids are not good biomarkers in Huntington’s disease

Free carnitine and branched chain amino acids are not good biomarkers in Huntington’s disease

ABSTRACT Background: Huntington’s disease (HD), caused by an expanded CAG repeat at HTT, has no treatment, and biomarkers are needed for future clinical trials. Objective: The objective of this study was to verify if free carnitine and branched chain amino acids levels behave as potential biomarkers...

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Main Authors: Raphael Machado CASTILHOS, Marina Coutinho AUGUSTIN, José Augusto dos SANTOS, José Luiz PEDROSO, Orlando BARSOTTINI, Roberta SABA, Henrique Ballalai FERRAZ, Fernando Regla VARGAS, Gabriel Vasata FURTADO, Marcia Polese-BONATTO, Luiza Paulsen RODRIGUES, Lucas Schenatto SENA, Carmen Regla VARGAS, Maria Luiza SARAIVA-PEREIRA, Laura Bannach JARDIM, Rede NEUROGENÉTICA
Format: Article
Language:English
Published: Thieme Revinter Publicações 2020-03-01
Series:Arquivos de Neuro-Psiquiatria
Subjects:
Biomarkers
Amino Acids, Branched-Chain
Carnitine
Huntington Disease
Weight Loss
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2020000200081&tlng=en
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