CellFM: a large-scale foundation model pre-trained on transcriptomics of 100 million human cells

CellFM: a large-scale foundation model pre-trained on transcriptomics of 100 million human cells

Abstract Single-cell sequencing provides transcriptomic profiling at single-cell resolution, uncovering cellular heterogeneity with unprecedented precision. Yet, current single cell data analysis suffers from the inherent data noises, batch effects, and sparsity, highlighting the requirement of a un...

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Main Authors: Yuansong Zeng, Jiancong Xie, Ningyuan Shangguan, Zhuoyi Wei, Wenbing Li, Yun Su, Shuangyu Yang, Chengyang Zhang, Jinbo Zhang, Nan Fang, Hongyu Zhang, Yutong Lu, Huiying Zhao, Jue Fan, Weijiang Yu, Yuedong Yang
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-59926-5
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https://doi.org/10.1038/s41467-025-59926-5

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