Plant-derived nodule-specific cysteine-rich peptides as potent antifungal agents against Cryptococcus neoformans: mechanisms of action, chimeric peptide enhancement, and immunomodulatory effects

Plant-derived nodule-specific cysteine-rich peptides as potent antifungal agents against Cryptococcus neoformans: mechanisms of action, chimeric peptide enhancement, and immunomodulatory effects

The basidiomycetous yeast Cryptococcus neoformans is classified among the four critical fungal pathogens due to its capability of inducing life-threatening meningitis in immunocompromised individuals, particularly AIDS patients. The increasing prevalence of antifungal resistance and limitations of c...

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Bibliographic Details
Main Authors: Bettina Szerencsés, Csaba Papp, Alexandra Pál, Sándor Jenei, Nelli Németh, Csaba Vágvölgyi, Ferhan Ayaydin, Gabriella Endre, Éva Kondorosi, Ilona Pfeiffer
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Current Research in Microbial Sciences
Subjects:
Antimicrobial peptide
Antifungal activity
Cryptococcus neoformans
Online Access:http://www.sciencedirect.com/science/article/pii/S2666517425000690
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