Leishmaniavirus-Dependent Metastatic Leishmaniasis Is Prevented by Blocking IL-17A.

Leishmaniavirus-Dependent Metastatic Leishmaniasis Is Prevented by Blocking IL-17A.

Cutaneous leishmaniasis has various outcomes, ranging from self-healing reddened papules to extensive open ulcerations that metastasise to secondary sites and are often resistant to standard therapies. In the case of L. guyanensis (L.g), about 5-10% of all infections result in metastatic complicatio...

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Main Authors: Mary-Anne Hartley, Eliane Bourreau, Matteo Rossi, Patrik Castiglioni, Remzi Onur Eren, Florence Prevel, Pierre Couppié, Suzanne M Hickerson, Pascal Launois, Stephen M Beverley, Catherine Ronet, Nicolas Fasel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-09-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1005852&type=printable
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https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1005852&type=printable

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