Epidermal growth factor receptor signaling governs the host inflammatory response to invasive aspergillosis

Epidermal growth factor receptor signaling governs the host inflammatory response to invasive aspergillosis

ABSTRACT The epidermal growth factor receptor (EGFR) has been identified as an epithelial cell receptor for Mucorales fungi and Candida albicans. Blocking EGFR with small molecule inhibitors reduces disease severity in mouse models of mucormycosis and oropharyngeal candidiasis. In contrast, cases of...

Full description

Saved in:
Bibliographic Details
Main Authors: Hong Liu, Jianfeng Lin, Quynh T. Phan, Vincent M. Bruno, Scott G. Filler
Format: Article
Language:English
Published: American Society for Microbiology 2024-12-01
Series:mBio
Subjects:
Aspergillus fumigatus
alveolar epithelial cell
small-airway epithelial cell
endocytosis
epidermal growth factor receptor
cytokine
Online Access:https://journals.asm.org/doi/10.1128/mbio.02671-24
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://journals.asm.org/doi/10.1128/mbio.02671-24

Similar Items