Association Between Preoperative Cognitive Performance and Postoperative Delirium in Older Patients: Results From a Multicenter, Prospective Cohort Study, and a Mendelian Randomization Study

Association Between Preoperative Cognitive Performance and Postoperative Delirium in Older Patients: Results From a Multicenter, Prospective Cohort Study, and a Mendelian Randomization Study

ABSTRACT This study evaluated the association between preoperative cognitive performance and postoperative delirium (POD) using a multicenter prospective cohort, and explored potential causality using Mendelian randomization (MR) analysis. We analyzed data from 2257 patients aged ≥ 75 years undergoi...

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Main Authors: Rao Sun, Shiyong Li, Changming Yang, Guiming Huang, Chunrong Tang, Wei Li, Zhongyuan Xia, Mingzhang Zuo, Ning Yang, Huiyu Luo, Kun Zhang, Huajun Li, Qingfeng Zeng, Chun Chen, Lan Wang, Rui Xia, Chuanbin Dong, Junmin He, Qiaoqiao Xu, Xinhua Li, Biyun Zhou, Shangkun Liu, Fang Luo, Zhiqiang Zhou, Ailin Luo
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:MedComm
Subjects:
cognitive impairment
Mendelian randomization
Mini‐Cog test
postoperative delirium
prospective cohort study
Online Access:https://doi.org/10.1002/mco2.70302
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https://doi.org/10.1002/mco2.70302

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