Comparative efficacy of preventive vs. therapeutic resveratrol in modulating gut microbiota and alleviating inflammation in DSS-induced colitis

Comparative efficacy of preventive vs. therapeutic resveratrol in modulating gut microbiota and alleviating inflammation in DSS-induced colitis

Abstract Background Inflammatory bowel disease (IBD) management remains challenging due to limited preventive strategies and the low bioavailability of therapeutic agents like resveratrol (RSV). While RSV exhibits anti-inflammatory properties, its preventive potential via gut microbiome modulation r...

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Main Authors: Senmei Qin, Zongjing Yang, Jinqing Lei, Qingli Xie, Linsui Jiang, Yuanyuan Fan, Yonggu Luo, Kecong Wei, Wei Luo, Bing Yu
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Immunology
Subjects:
Resveratrol
Inflammatory bowel disease
Gut microbiota
Macrophage polarization
TLR4/NF-κB pathway
Online Access:https://doi.org/10.1186/s12865-025-00718-3
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https://doi.org/10.1186/s12865-025-00718-3

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